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Wednesday, October 14, 2009
Genetic approaches to addiction: genes and alcohol
Addiction. Author manuscript; available in PMC 2009 September 1. Published in final edited form as: Addiction. 2008 September; 103(9): 1414–1428.
Alcoholism is a chronic relapsing disorder with an enormous societal impact. Understanding the genetic basis of alcoholism is crucial to characterize individuals' risk and to develop efficacious prevention and treatment strategies.
We examined the available scientific literature to provide an overview of different approaches that are being integrated increasingly to advance our knowledge of the genetic bases of alcoholism. Examples of genes that have been shown to influence vulnerability to alcoholism and related phenotypes are also discussed.